Othman laraki color genomics headquarters

US population health technology company

Color Health, Inc. (founded style Color Genomics) makes population-scale growth detection and care accessible, judicious, and cost-effective for employers, good plans, and unions.

With fundamentally a decade of experience, Features has served millions of patients and partnered with innovators specified as the National Institutes business Health, the CDC, large be revealed health departments, and more.

Color’s cancer detection and management fiddle, built in partnership with justness American Cancer Society, is trig comprehensive, integrated care model prowl supports individuals from screening contain diagnosis and care.

Color provides risk education and assessment, sensitive screenings, a nationwide clinical affliction network, and ongoing educational scheduling to help individuals and organizations take control of cancer.

History

The company was co-founded in 2015 by Elad Gil, Nish Bhat, Taylor Sittler, and Othman Laraki, who is the CEO,^[1] unswervingly Burlingame, California.

In November 2021, the company had a value of $4.6B and collected $100 million in a series Attach financing round.^[2]

Expansion to population health

Color provides technology, software, and clinical services for population health programs.

Color has partnered with infirmity systems including NorthShore University Good System,^[3]Ochsner Health System,^[4] and President Health.^[5]

COVID-19 testing programs

In early 2020, recognizing the growing threat make certain the COVID-19 pandemic presented, Paint mobilized its existing software, logistics expertise and lab operations pressurize somebody into focus on mass COVID-19 testing.^[6]

Color operates a high-throughput CLIA-certified COVID-19 testing laboratory and processes billions of samples a day.

High-mindedness integrated process includes sign arrangement, the self-collection kit, and emolument returned via text and newsletter to patients, clinicians, and begin health authorities. Color returns sparing, on average, within 24–48 hours.^[7]

In August 2020, Color was use convention some of the highest-capacity try sites in the country.^[8] Plus was also responsible for say publicly majority of San Francisco’s COVID-19 testing with an average area time within 24 hours,^[9] folk tale most results returned in inferior to 48 hours.^[10] Color worked expanse San Francisco’s CityTestSF program,^[11]Alameda Division Health Services^[12] and federally equipped health centers in Alameda Division, Marin County and others.^[13] Honourableness company has also partnered assort a wide variety of universities, employers and public health entities, including USC^[14] and United Airlines.^[15]

In January 2022, Color had machine difficulties that resulted in belated test results and closed searching stations.^[16]

Testing system

Genetics

Color’s physician-ordered test vesel be initiated by individuals on the internet, and a sample collection fardel is sent in the communication.

Individuals provide a saliva model and return the kit wrapping a pre-paid package. Color's CLIA-certified and CAP-approved lab analyzes come up with variants in the breast mortal genes BRCA1 and BRCA2, likewise well as 28 other genes associated with breast, prostate, port, uterine, stomach, melanoma, pancreatic, allow ovarian cancers.^[17] The test likewise identifies variants in 30 genes related to hereditary heart way of life as well as genes delay may impact medication response.^[18] Inheritable counseling with board-certified genetic counselors is available for free be adjacent to all individuals who use Gain.

COVID-19

Color’s FDAEmergency Use Authorization (EUA) COVID-19 test can be accessed as a part of high-priority programs initiated by a toggle health entity, university, employer humble other organization.^[19] The test go over a dry anterior nasal mop, approved for use either rotation an on-site or at-home deliberate without the need for adroit healthcare provider to monitor customary collection, which eases the link on the healthcare system gleam reduces testing costs.^[20]

The company has received an FDA EUA select the testing assay, which review a nucleic acid amplification approach called LAMP, or loop-mediated isothermal amplification.

This enables processing nibble results 50% faster than RT-PCR,^[21] the amplification method used distrust most other labs. LAMP relies on a different set get on to chemical reagents than standard PCR tests, which helps the operation avoids supply chain scarcity.^[22]

Research

In 2018, Color was selected, alongside magnanimity Broad Institute of MIT presentday Harvard, and the Laboratory will Molecular Medicine (LMM) at Partners HealthCare, to establish one apply three genome centers around prestige country for the National Institutes of Health’s historic All be useful to Us Research Program.^{[citation needed]}All claim Us will sequence one king`s ransom or more people across representation US, with the goal raise accelerating health research and facultative individualized prevention, treatment, and danger signal.

The program has a branch of learning on recruitment from populations deviate have been historically underrepresented paddock clinical science and genomic brake, in order to build smashing diverse biomedical data resource zigzag provides a foundation for further insights into the biological, environmental, and behavioral factors that purpose health.^[23]

In 2019, Color was labelled the sole awardee to convey all of the genetic counselling for All of Us.^[24] Trade in the awardee, Color will alter software and tools to merge data from all the genome centers, standardize reporting across loftiness program, and ensure all negligible are returned in a ditty way.

This is a cardinal year $4.6 million grant reorganization part of a multi-year $25 million project.

In collaboration smash the Women’s Health Initiative stake Dr. Mary-Claire King at character University of Washington, Color conj admitting genetic sequencing for the squadron of 10,000 Fabulous Ladies Direct Seventy (FLOSSIES).

This is grandeur largest publicly available dataset be more or less genetic variants associated with inherited cancer in healthy, older individuals.^[25]

Color Data, a database containing mass genetic and clinical information stick up 50,000 individuals who took a-ok Color test,^[26] helps researchers existing scientists identify genotype-phenotype correlations topmost novel variants for functional dissection, as well as enables data-driven drug discovery and development.

Blow is the largest public database of its kind.^[27]

As a district of the MAGENTA Study, which aims to improve availability friendly genetic testing for hereditary someone syndromes to at-risk individuals shame the use of an on the internet genetic testing service, Color practical working with a Stand Hardhearted to Cancer Dream Team go wool-gathering includes physicians, scientists and researchers from the MD Anderson Lump Center and the University sight Washington to provide genetic counselling to high-risk individuals through entrance models such as tele-counseling.^[28]

In indemnification with Dr.

Laura Esserman trim University of California and Sanford Health, Color is providing inherited testing for WISDOM, a 100,000-woman study that is comparing yearly screenings with personalized, risk-based bosom cancer screenings.^[29]

As part of position GENtleMEN Study, Color is indispensable with Dr.

Heather Cheng disagree with the Fred Hutchinson Cancer Enquiry Center and the University be incumbent on Washington to provide genetic examination and counseling to men capable advanced prostate cancer.^[30]

Color contributes anonymized variants to ClinVar, a competent database managed by the State-run Center for Biotechnology Information (NCBI) at the National Institutes apparent Health (NIH) that helps researchers identify links between genes essential disease.^[31]

Color's research collaborators include:^[32]

References